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AneurysmFlow

Cerebral aneurysm flow quantification

Assessing impact of embolization devices, like flow diverters, on blood flow right after deployment is crucial. AneurysmFlow is designed to provide relevant information based on quantification of blood flow changes.

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Media Gallery

  • Relevant information about blood vessel flow

    Relevant information about blood vessel flow
    Flow diverters are being increasingly used to treat cerebral aneurysms, but flow diversion procedures remain challenging. Only 76% of all aneurysm flow diversion cases result in thrombosis after 6 month follow-up,¹ which poses a risk to the patient. Several authors have shown that the flow pattern inside aneurysms is considered one of the parameters that can be used to predict rupture and clotting.²,³AneurysmFlow is the first tool that visualises and quantifies flow changes in the parent vessel and aneurysm before and after flow diverter deployment. It also provides a unique metric – the Mean Aneurysm Flow Amplitude (MAFA) ratio.

  • Expanding functional understanding

    Expanding functional understanding
    Currently, a combination of digital subtraction angiography (DSA) and three-dimensional rotational angiography (3DRA) is the gold standard for imaging vascular lesions, but it provides limited functional information about flow. AneurysmFlow uses novel algorithms based on the optical flow principle to convert information from a 3DRA acquisition and 2D DSA flow sequences into quantitative flow values. These values are used to visualise and quantify flow dynamics before and after flow diverter deployment in cerebral aneurysms.

  • Enhances decision making

    Enhances decision making
    AneurysmFlow automatically measures the following parameters within the region of interest defined: time averaged arterial flow, time and spatially averaged projected aneurysm flow, and Mean Aneurysm Flow Amplitude (MAFA) ratio. Users can also view the following information as graphs: time dependent arterial flow and time dependent, spatially averaged projected aneurysm flow.

  • New information with Mean Aneurysm Flow Amplitude ratio

    New information with Mean Aneurysm Flow Amplitude ratio
    The Mean Aneurysm Flow Amplitude (MAFA) ratio represents the change in blood flow in the aneurysm after flow diverter deployment. The MAFA ratio is derived by comparing the average projected velocity of the blood flow in the aneurysm before and after flow diverter deployment. This ratio is corrected for average velocity change of the blood flow in the primary feeding vessel to the aneurysm.

  • Step-by-step workflow

    Step-by-step workflow
    AneurysmFlow supports endovascular treatment of saccular cerebral aneurysms with embolisation devices, such as flow diverters. Data acquisition can be controlled at the tableside during the normal workflow, while analysis is performed in the control room.

    Documents

    Related products

    ¹ Brinjikji W, Murad MH, Lanzino G. et al. Endovascular treatment of intracranial aneurysms with flow diverters: a meta-analysis. Stroke. 2013;44:442–447.

    ² Augsburger L, et al. Methodologies to assess blood flow in cerebral aneurysms: Current state of research and perspectives. J Neurorad. 2009;36:270–277.

    ³ Sforza DM, Putman CM, Cebral JR. Hemodynamics of Cerebral Aneurysms. Annu Rev Fluid Mech. 2009; 41:91–107.

     

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