Philips introduces next generation interventional oncology solution OncoSuite* for advanced tumor analysis and therapy in Europe

Optimized to support minimally invasive treatment of liver cancer – the second most deadly cancer, accounting for 745,000 annual deaths worldwide [1]
Features world’s first optimized imaging for radiopaque beads (LC Bead LUMITM)** for tumor treatment, minimizing damage to surrounding healthy tissue and organs
OncoSuite enables a unique complete coverage of the liver to visualize peripheral hepatic tumors

September 9, 2016

Amsterdam, the Netherlands and Barcelona, Spain – Royal Philips (NYSE: PHG, AEX: PHIA) today announced that it will unveil its latest innovation in interventional oncology at the 2016 Cardiovascular and Interventional Radiological Society of Europe annual meeting (CIRSE 2016), which will be held in Barcelona (Spain) from September 10 until 14. Philips’ next generation interventional oncology solution OncoSuite will enable physicians to provide analysis and minimally invasive, targeted treatment of tumor lesions reducing the impact to healthy tissue. It offers clinicians a better view of the treatment targets for informed decision making, while performing the procedure.

“While OncoSuite can be used for a number of different cancers including bone, kidney and lung, the solution and its specific tools have been optimized for the treatment of patients with liver cancer,” said Dr Jeff Geschwind, Chairman and Chief of the Department of Radiology and Biomedical Imaging at the Yale School of Medicine. “Given the steady increase in the prevalence of non-alcoholic fatty liver disease and liver cancer [2], the development and availability of new technology is much needed to provide interventional oncologists with a breakthrough that allows best possible treatment for these patients.”

Dr. Geschwind continued: “What matters most in these cases, is the ability to visualize the liver tumors, even small ones, during the procedure and to approach them in a very targeted way to maximize the therapeutic outcome, while avoiding the destruction of healthy liver tissue. OncoSuite is designed to help us see, reach and treat liver cancer in a better way [3-5].”

OncoSuite is Philips’ integrated solution to enhance tumor embolization and ablation procedures with Philips’ interventional X-ray systems. It is the only platform in the industry that supports both procedures enabling physicians to target multiple tumor lesions simultaneously. OncoSuite comprises Philips’ innovative product offerings for enhanced imaging (XperCT Dual), live 3D image guidance for tumor embolization (EmboGuide) and live 3D image guidance for tumor ablation (XperGuide). It is yet another example of Philips’ Image Guided Therapy solutions that advances minimally invasive procedures by helping physicians decide, guide, treat and confirm the right therapy for each patient.

“Minimally invasive, image-guided interventional oncology procedures are a highly effective option for patients who cannot be treated through conventional techniques such as surgery, chemotherapy or radiation therapy,” said Ronald Tabaksblat, Business Leader Image Guided Therapy Systems at Philips. “Interventional oncology procedures are rapidly increasing and OncoSuite provides the first complete interventional oncology portfolio for interventional radiologists, enabling physicians to see the entire tumor and its feeder vessels to directly target treatment avoiding healthy tissue.”

The next generation
OncoSuite allows targeted treatment of an entire tumor and its feeder vessels, sparing surrounding tissue or organs. The innovative Open Trajectory function within XperCT Dual enables better centering of the liver with significantly improved visualization during the procedure of peripheral hepatic tumors in a single sweep [6]. This feature provides a more targeted field of view making it possible to effectively scan larger patients. Previously, with the traditional geometric movement of the C-arm of the interventional X-ray system, part of the liver image was truncated and larger patients required multiple scans to visualize tumors in the periphery of the liver.

Embolization procedures involve blocking the arteries feeding a tumor with beads to deprive it of nutrients and oxygen. They require the insertion of a catheter, which must be guided to the tumor site with the aid of live image-guidance. BTG and Philips have been working in close collaboration on the visualization benefits of radio-opaque beads in combination with image-guided therapy. Together the companies have calibrated LC Bead LUMITM and Philips Live Image Guidance Software to help interventional radiologists and multi-disciplinary teams to visualize better treatment options for patients with liver cancer. As a result, the next generation OncoSuite also features the world’s first optimized imaging for LC Bead LUMITM that provides real-time visible confirmation of bead location during embolization procedures [7]. In addition, the new Wiper Movement functionality improves workflow with automatic Dual Phase imaging, helping physicians to acquire two 3D cone beam CT datasets at different times of the procedure in a single step.

The next generation OncoSuite reflects Philips’ commitment to deliver better, more personalized care to patients, while reducing healthcare costs. For more information on Philips presence at the CIRSE Congress 2016, please visit here and follow the #CIRSE2016 conversation @PhilipsLiveFrom throughout the event. OncoSuite and Philips’ full suite of integrated radiology solutions will also be featured at the upcoming 2016 RSNA annual meeting in Chicago (US) later this year. For continuous updates on Philips’ presence at RSNA 2016, please visit here.

References and notes:

* OncoSuite is the combination of Philips’ innovative product offerings XperCT Dual, EmboGuide and XperGuide. XperCT Dual rel3.3 with Open Trajectory and XperCT for LUMI optimized imaging is not yet CE marked, and not yet available for delivery.

** LC Bead LUMITM is the official trademark of BTG (Biocompatibles UK Ltd.) and is not available as part of Philips’ OncoSuite.

[1] Stewart, BW, Wild CW. World Cancer Report. 2014. Available at:
https://shop.iarc.fr/products/wcr2014 Accessed August 2016

[2] Tucker, ME. Fatty Liver Disease Surging as Liver Cancer Cause. 2015. Available at:
http://www.medscape.com/viewarticle/843733 Accessed August 2016

[3] Loffroy R, et al. Intraprocedural C-arm dual-phase cone-beam CT: can it be used to predict short-term response to TACE with drug-eluting beads in patients with hepatocellular carcinoma? Radiol. 2013 Feb;266(2):636-48

[4] Miyayama S, et al. Efficacy of automated tumor-feeder detection software using cone-beam computed tomography technology in transarterial embolization through extrahepatic collateral vessels for malignant
hepatic tumors. Hepatol Res. 2016 Feb;46(2):166-73

[5] Schernthaner RE, et al. Improved Visibility of Metastatic Disease in the Liver During Intra-Arterial Therapy Using Delayed Arterial Phase Cone-Beam CT. Cardiovasc Intervent Radiol. 2016 Jul 5. [Epub ahead
of print]

[6] Schernthaner RE, et al. Feasibility of a modified cone-beam CT rotation trajectory to improve liver periphery visualization during transarterial chemoembolization. Radiology. 2015;277(3):833–41

[7] Levy EB, et al. First Human Experience with Directly Image-able Iodinated Embolization Microbeads. Cardiovasc Intervent Radiol. 2016 Aug;39(8):1177-86

For further information, please contact:

Steve Klink

Philips Group Communications

Tel: +316 10888824

E-mail: steve.klink@philips.com

Fabienne van der Feer
Philips Image Guided Therapy
Tel: +31 6 22698001
E-mail: fabienne.van.der.feer@philips.com

About Royal Philips

Royal Philips (NYSE: PHG, AEX: PHIA) is a leading health technology company focused on improving people's health and enabling better outcomes across the health continuum from healthy living and prevention, to diagnosis, treatment and home care. Philips leverages advanced technology and deep clinical and consumer insights to deliver integrated solutions. Headquartered in the Netherlands, the company is a leader in diagnostic imaging, image-guided therapy, patient monitoring and health informatics, as well as in consumer health and home care. Philips' health technology portfolio generated 2015 sales of EUR 16.8 billion and employs approximately 69,000 employees with sales and services in more than 100
countries. News about Philips can be found at www.philips.com/newscenter