Philips Pharma Solutions

A combined focus on device technology and aerosol drug delivery excellence.

Your drug is our number one priority. We offer a range of devices and drug delivery technologies - developed through nearly 40 years of innovation - giving you flexibility to meet both your clinical and financial requirements. If your drug requires unique features or functions, we can work with you to create a custom device to meet your needs.

Our lab services combine the facilities, methods and equipment you can count on to deliver scientifically validated data, with our staff’s deep knowledge of the regulatory process. So you can be sure your drug is optimally performing, and your submission plan is expertly designed.

Bringing an aerosol drug to market quickly and cost-effectively takes a successful combination of:

Clinical efficacy
Testing accuracy
Regulatory expertise

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Nebulizers

The aerosol delivery systems that Philips offers include a breadth of features that ensure efficient aerosol drug delivery, in simple to use, portable devices. The devices below feature vibrating mesh technology.

InnoSpire Go

Designed to reduce overall treatment burden
Treatment in 4 minutes¹
Unique two-part design
Built-in rechargeable battery

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I-neb

Adaptive aerosol delivery to deliver precise and repeatable doses²
Drug specific capability
Black and white screen functionality
Customization options

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I-neb Advance

Adaptive aerosol delivery to deliver precise and repeatable doses¹
Ergonomic usability
LCD Screen functionality
Customization options
Data logging capabilities to aid adherence monitoring
Only available for clinical trial

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Micro

Delivery of lower fill volumes
Breath-actuated
Only available for Clinical trial

Unsure which device is right for your drug?

Use our device decision tree to help determine which device can best suit your aerosol drug delivery needs.

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Aerosol services

Our own state-of-the-art, regulatory compliant R&D and lab facilities deliver comprehensive drug and device testing in clinical performance, drug delivery integrity, and data generation for trials and submission. Philips advanced aerosol devices and lab facilities offer pharmaceutical companies an in-depth level of support from every step of the development process - from pre-test to market.

Testing and support in liquid aerosol delivery

In our state-of-the-art aerosol science laboratory, our scientists provide guidance for the ideal testing needed for clinical trials, regulatory submissions and approvals. Our laboratory capabilities include:

Expert, experienced staff

Our established team of scientists have vast experience and expertise in inhalation science, including aerosol testing, analytical, microbiology and regulatory requirements for device and drug submissions.

Cutting-edge facilities

Our facilities are designed for testing, analytics and microbiology, and precisely controlled for temperature and humidity. We offer a comprehensive range of testing equipment, methods and measurements.

Full standards compliance

We operate in full compliance to cGLP standards, offering aerosol testing performed to specific device or pharmaceutical regulations, and against validated SOPs/Methods.

A proven process

Our feasibility testing process includes key steps to validate your drug and prepare it for regulatory submission. Our Material Transfer Agreements include strict controls to ensure your compound is handled with confidentiality, protecting your IP while in our control.

Stage 1

Matching device and drug

We explore and test the suitability of our devices to your drug, to determine which is the appropriate device to meet critical clinical parameters, including particle size, delivery time, dose and drug residual.

Stage 2

Assessing performance

We assess the performance of the device in simulated breathing conditions to determine the effectiveness of the device in delivering your drug to a patient, including integrity after delivery, particle size, delivered dose and delivery time.

Stage 3

Preparing for submission

We generate the necessary data required for submission, by conducting quality assurance testing on the device, your drug and our drug delivery test results in stages 1 and 2.

Setting you up for success
Our aerosol testing laboratory capabilities can benefit your drug product by:

Helping you to find the right device for your drug to maximize efficacy and speed to market

Pre-testing your new chemical entities before launching costly clinical trials

Identifying the ideal approach for both testing and data capture for successful regulatory submission

Delivering trial results that are precise and reproducible

Delivering data at GLP standards, with analytical and technical documentation that support for regulatory submissions

See how we support pharmaceutical partners in bringing aerosol drugs to market with life-changing devices. Philips offer devices that are designed to lessen the overall treatment burden for patients.

Clinically proven mesh from hospital to home

Our advanced aerosol delivery products are the only home-use devices featuring Aerogen Vibronic^® meshes^*, the same unique palladium vibrating mesh technology used in hospital ventilators worldwide to deliver aerosolized medications. The central aperture plate is just 5mm in diameter and is perforated with 1000 precision formed holes, that vibrate at 128,000 times per second, to produce the optimum particle size for deep lung penetration.

*excluding I-neb

Mesh nebulizer capabilities in aerosolizing a wide range of novel pharmaceutical formulas

Mesh devices should be considered as a first choice when looking at inhaled drug delivery. Devices with different modes of operation (active and passive vibrating mesh) are capable of delivering a variety of pharmaceutical formulations with a wide range of physichemical characteristics.

Presented by Philips Respironics at ERS, September 3rd-7th 2016. London UK

View capabilities graph (91.0KB)

Patient testimonial

Meet Anna, a 7 -year old cystic fibrosis patient, who uses the Philips Respironics I-neb AAD system nebulizer to help manage her condition.

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Philips also offer a wide range of compressor nebulizers and accessories utilizing the proven, high efficiency, SideStream technology.

Explore the RDD Catalogue

Clinical expertise and leadership in Advanced Aerosol Delivery

Publications

I-neb AAD System

Domiciliary Experience of the Target Inhalation Mode (TIM) Breathing Maneuver in Patients with Cystic Fibrosis Denyer J, Black A, Nikander K, Dyche T, Prince I. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S45-S54	Mode of Breathing—Tidal or Slow and Deep—through the I-neb Adaptive Aerosol Delivery (AAD) System Affects Lung Deposition of 99mTc-DTPA Nikander K, Prince I, Coughlin S, Warren S, Taylor G. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S37-S43
Evaluation of Patient-Reported Outcomes and Quality of Life with the I-neb AAD System in Patients with Chronic Obstructive Pulmonary Disease Goodman N, Morgan M, Nikander K, Hinch S, Coughlin S. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S61-S70	The Adaptive Aerosol Delivery System in a Telehealth Setting: Patient Acceptance, Performance and Feasibility Nikander K, Denyer J, Dodd M, Dyche T, Webb K, Weller P, Stableforth D. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S21-S27
Evaluation of the Target Inhalation Mode (TIM) Breathing Maneuver in Simulated Nebulizer Therapy in Patients with Cystic Fibrosis Denyer J, Prince I, Dixon E, Agent P, Pryor J, Hodson M. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S29-S36	The Adaptive Aerosol Delivery (AAD) Technology: Past, Present, and Future. Denyer J, Dyche T. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S1-S10
In Vitro Characterization of the I-neb Adaptive Aerosol Delivery (AAD) System Hardaker LEA, Hatley RHM. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S11-S20	The I-neb Adaptive Aerosol Delivery System Enhances Delivery of α1-Antitrypsin with Controlled Inhalation Geller DE, Kesser KC. J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S55-S59
OptiChamber Diamond Valved Holding Chamber In Vitro Characterization of the OptiChamber Diamond Valved Holding Chamber Hatley RHM, von Hollen D, Sandell D, Slator L. J Aerosol Med Pulm Drug Deliv. 2014; 27(Suppl 1):S24-S36	Development of Inhaled Pharmaceuticals Rethinking the Paradigm for the Development of Inhaled Drugs Pritchard J. International Journal of Pharmaceuticals. 2015; 496:1069-1072

Domiciliary Experience of the Target Inhalation Mode (TIM) Breathing Maneuver in Patients with Cystic Fibrosis

Denyer J, Black A, Nikander K, Dyche T, Prince I.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S45-S54

Evaluation of Patient-Reported Outcomes and Quality of Life with the I-neb AAD System in Patients with Chronic Obstructive Pulmonary Disease

Goodman N, Morgan M, Nikander K, Hinch S, Coughlin S.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S61-S70

Evaluation of the Target Inhalation Mode (TIM) Breathing Maneuver in Simulated Nebulizer Therapy in Patients with Cystic Fibrosis

Denyer J, Prince I, Dixon E, Agent P, Pryor J, Hodson M.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S29-S36

In Vitro Characterization of the I-neb Adaptive Aerosol Delivery (AAD) System

Hardaker LEA, Hatley RHM.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S11-S20

Mode of Breathing—Tidal or Slow and Deep—through the I-neb Adaptive Aerosol Delivery (AAD) System Affects Lung Deposition of 99mTc-DTPA

Nikander K, Prince I, Coughlin S, Warren S, Taylor G.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S37-S43

The Adaptive Aerosol Delivery System in a Telehealth Setting: Patient Acceptance, Performance and Feasibility

Nikander K, Denyer J, Dodd M, Dyche T, Webb K, Weller P, Stableforth D.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S21-S27

The Adaptive Aerosol Delivery (AAD) Technology: Past, Present, and Future.

Denyer J, Dyche T.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S1-S10

The I-neb Adaptive Aerosol Delivery System Enhances Delivery of α1-Antitrypsin with Controlled Inhalation

Geller DE, Kesser KC.

J Aerosol Med Pulm Drug Del. 2010;23(Suppl 1):S55-S59

OptiChamber Diamond Valved Holding Chamber

In Vitro Characterization of the OptiChamber Diamond Valved Holding Chamber

Hatley RHM, von Hollen D, Sandell D, Slator L.

J Aerosol Med Pulm Drug Deliv. 2014; 27(Suppl 1):S24-S36

Development of Inhaled Pharmaceuticals

Rethinking the Paradigm for the Development of Inhaled Drugs

Pritchard J.

International Journal of Pharmaceuticals. 2015; 496:1069-1072

Download a complete list of our publications (144.0KB)

@PhilipsHealth

References

1 Using 2.5ml Salbutamol

2 Nominal 0.5ml chamber delivered Salbutamol to filter in the range 534.1-591.5uL

Philips Pharma Solutions

A combined focus on device technology and aerosol drug delivery excellence.

Contact information

Nebulizers

InnoSpire Go

I-neb

I-neb Advance

Micro

Unsure which device is right for your drug?

Aerosol services

Testing and support in liquid aerosol delivery

Expert, experienced staff

Cutting-edge facilities

Full standards compliance

A proven process

Stage 1

Stage 2

Stage 3

Setting you up for success
Our aerosol testing laboratory capabilities can benefit your drug product by:

See how we support pharmaceutical partners in bringing aerosol drugs to market with life-changing devices. Philips offer devices that are designed to lessen the overall treatment burden for patients.

Clinically proven mesh from hospital to home

Mesh nebulizer capabilities in aerosolizing a wide range of novel pharmaceutical formulas

Patient testimonial

Explore more

Philips also offer a wide range of compressor nebulizers and accessories utilizing the proven, high efficiency, SideStream technology.

Clinical expertise and leadership in Advanced Aerosol Delivery

Publications

Related products

Respiratory drug delivery

Ventilation

Oxygen

News

@PhilipsHealth

Philips Pharma Solutions

A combined focus on device technology and aerosol drug delivery excellence.

Contact information

Nebulizers

InnoSpire Go

I-neb

I-neb Advance

Micro

Unsure which device is right for your drug?

Aerosol services

Testing and support in liquid aerosol delivery

Expert, experienced staff

Cutting-edge facilities

Full standards compliance

A proven process

Stage 1

Stage 2

Stage 3

Setting you up for success Our aerosol testing laboratory capabilities can benefit your drug product by:

See how we support pharmaceutical partners in bringing aerosol drugs to market with life-changing devices. Philips offer devices that are designed to lessen the overall treatment burden for patients.

Clinically proven mesh from hospital to home

Mesh nebulizer capabilities in aerosolizing a wide range of novel pharmaceutical formulas

Patient testimonial

Explore more

Philips also offer a wide range of compressor nebulizers and accessories utilizing the proven, high efficiency, SideStream technology.

Clinical expertise and leadership in Advanced Aerosol Delivery

Publications

Related products

Respiratory drug delivery

Ventilation

Oxygen

News

@PhilipsHealth

Setting you up for success
Our aerosol testing laboratory capabilities can benefit your drug product by: