Dermatology

Dermatology phototherapy solutions
Focused on providing gentle and effective dermatology therapies

Ease and efficacy count when treating chronic skin conditions


Dermatology conditions impact the physical and psychological well-being of patients of all ages all around the world. Care protocols can often entail repeated office visits and time-consuming therapies that are difficult to integrate into daily routines. In addition, patients are confronted with potential side effects that might result in low treatment compliance and make many inflammatory skin diseases difficult to treat.
 

At Philips, we are committed to providing innovative dermatology therapies through research, clinical validation, patient input and the optimization of leading technologies. Our products are designed to offer patients treatment options that are gentle, effective, convenient and easy to use.

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Dr Ljubomir B Novaković FRCP 
Gives his opinion on Blue LED Light phototherapy 

Blue LED light therapy for psoriasis sufferer's


Dr Ljubomir B Novaković FRCP Consultant Dermatologist, Queen Elizabeth Hospital and Honorary Consultant Dermatologist, Department of Photodermatology, St John's Institute of Dermatology, Guy’s & St Thomas’ Hospital, London

 

Phototherapy with ultraviolet (UV) light is a well-established and effective treatment for psoriasis. It is usually a hospital based service as the use of UV radiation requires supervision by qualified staff because of its possible side effects, e.g. burning.

 

Now, Philips has introduced a UV-free light device, BlueControl Advance®, which does not include chemicals or cortisone, and is the first at home psoriasis treatment.

What is Philips BlueControl Advance® and how does it work?
Philips BlueControl Advance® emits visible blue light of 453 nm from a light-emitting diode (LED) source with a high output of 200 mW/cm2. The wearable device utilises the specially developed LEDs set to an ideal wave length to activate the natural healing processes and, blue light reduces the proliferation of keratinocytes.1 It has also been shown to have anti-inflammatory properties by modulating the T–cell immune response in vitro.2 The UV-free therapy is a gentle and effective way of  managing psoriasis around patient’s lifestyles.
Who is Philips BlueControl Advance® aimed at?
Philips BlueControl Advance® is designed for treatment of patients with mild to moderate plaque psoriasis that appears on arms and legs. As the device treats an area of 40 cm2 it is recommended to wear for 15 minutes per plaque, per day.
Is blue LED light therapy clinically proven to help psoriasis?
Clinical studies have confirmed the positive effects of blue LED light on psoriasis plaque symptoms such as redness, scaling and thickness. Over 12 weeks of treatment the plaque symptoms improved significantly for patients in the clinical study. In some patients, a complete clearance of the plaque was observed. During the treatment free follow-up phase of one month, plaque symptoms improved slightly further, rather than worsened. 83% of patients rated the usability and comfort of the device as ideal or excellent 3.
How is Philips BlueControl Adavnce® used?

Philips BlueControl Advance® device is attached to the skin affected with plaque psoriasis on the limbs with an adjustable textile strap. It automatically switches off after 15 minutes This is repeated 5-7 times per week for the first month and there after 3 times per week for a further couple of months.

 

Patients are advised to moisturise the skin after treatment.

Are there any side effects?
The treatment with blue light is well tolerated and there are no reported side effects apart from mild and transient hyperpigmentation.
How does the cost compare to other treatments?
A recent study in the Netherlands has shown that blue light therapy in the treatment of mild to moderate psoriasis was associated with cost savings when compared with the combined formulation of calcipotriol/betamethasone gel. This has been based on modelling in the Dutch Health Economy.5
Should Philips BlueControl Advance be used in combination with alternative topical treatments?

Philips BlueControl Advance® is the most recent addition to the phototherapy armamentarium in the treatment of mild to moderate plaque psoriasis. Studies have reported on its effectiveness and lack of acute side effects. It is convenient for use at home.

 

Although it can be used on its own, as with other forms of phototherapy, it may be considered in combination with a vitamin d topical.

References

 

1. http://www.jidonline.org/article/S0022-202X(15)34519-X/pdf ( Joerg Liebmann, Matthias Born, Victoria Kolb-Bachofen, Blue-Light Irradiation Regulates Proliferation and Differentiation in Human Skin Cells, In Journal of Investigative Dermatology, Volume 130, Issue 1, 2010, Pages 259-269, ISSN 0022-202X, https://doi.org/10.1038/jid.2009.194.

 

2. http://onlinelibrary.wiley.com/doi/10.1111/exd.12193/full (Fischer, M. R., Abel, M., Lopez Kostka, S., Rudolph, B., Becker, D. and von Stebut, E. (2013), Blue light irradiation suppresses dendritic cells activation in vitro. Exp Dermatol, 22: 558–560. doi:10.1111/exd.12193). 

 

3. Philips conducted two clinical trials in partnership with the University Hospital of Aachen as part of a three year project from 2007-2009. Forty-seven patients with mild Pv were randomized for receiving high-intensity blue light treatment (HI: 453nm LED, 200 mW/cm(2), n = 24) and low-intensity treatment (LI: 453 nm LED, 100 mW/cm(2), n = 23) of one Pv plaque for 12 weeks.

 

4. https://www.futuremedicine.com/doi/full/10.2217/cer-2017-0007 Ansaripour, Amir & Bing Thio, Hok & Maessen, Rob & Redekop, Ken. (2017). The cost–effectiveness of blue-light therapy in the treatment of mild-to moderate psoriasis. Journal of Comparative Effectiveness Research.

BlueControl psoriasis treatment
Wearable, UV-free blue LED light phototherapy for the treatment of psoriasis vulgaris.

Blue LED light
Potential for a range of medical applications across the health continuum

Blue light has a wavelength of 400–490 nm and is part of the light spectrum that is visible to the human eye. Blue light does not contain any UV-radiation and penetrates deeply into the skin. It is known that blue light has positive effects on the human body. LEDs are known for their energy efficiency, compact design and stability. The combination – blue LEDs – is a promising and powerful tool for medical applications. Research shows that LEDs used for medical treatments require special features that exceed those of conventional LEDs, including high intensities and tailored adjustments such as pulsed LED light. With blue LEDs optimized specifically for health applications, patients receive the benefits of phototherapy through the gentle, natural process-inducing characteristics of LED light in the visible blue spectrum.

Blue LED light therapy at a glance
 

  • UV-free blue LED light (453 nm) is non-toxic for the skin1, 2
  • No active ingredients or chemical substances are required
  • Avoids side effects medications may have
  • Stimulates natural processes in the body
  • LEDs are highly energy efficient, long-lasting and compact